Biopharmaceuticals have revolutionised the treatment of chronic diseases and its industry is under considerable pressure to produce “first-in-class medicines” in a cost-effective and safe manner. 
Join STACCATO early stage researchers in the podcast series to learn about their experience and research on single-cell analysis to develop new manufacturing methods for biopharmaceuticals.

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With this episode, Kelly and Brian, early stage researchers (ESR11 and ESR5) are introducing STACCATO, an EU-funded PhD training program. They are talking about, what is an industrial PhD and how is living and working in Sweden. In addition, they explain the principle of single-cell transcriptome analysis and how we are using this method for our PhD projects.

With this episode, join James Clubb, early stage researcher (ESR4), as he sits down with his father and discusses all things STACCATO. They talk about the promise of oncolytic virotherapy, a new promising treatment for cancer and the manufacturing bottle-neck which limits sufficient supply for trials, hospitals and patients. James also explains how single-cell transcriptome analysis is being used to guide gene-editing strategies, to improve production efficiency of cell lines used in oncolytic virus biomanufacturing.

In this episode, STACCATO ESR2 Alan Foley, an early stage researcher in the STACCATO project explains his research to science graduate, Ciara. Join this light conversation on mitochondrial DNA, Single-cell analysis and DNA analysis and learn what exactly these are.

In this episode, you will the true PhDs meeting. Two early stage researchers from STACCATO, Filip (ESR9) and Elham (ESR10) are talking to Naphang and Alex, two PhD fellows who explain their projects and share the experiences they had while working in the Lab. While they both work in CAR-T cell field, they have unique and exciting projects. Alex has experience with both academic and industrial sectors and he gives us an overview of how they might differ. Naphang explains how he manages in-vivo experiments and gives some tips on how to write a PhD thesis.

In this episode, Teresa, an early stage researcher (ESR1) in the STACCATO consortium, introduces us to Padraig Fitzgerald, BD’s senior R&D  director. Padraig introduces BD, their research centre in Ireland, and why they became a partner in the STACCATO consortium. We then dive into some recent results that Teresa has generated as part of her PhD project,  which uses many of BD’s exciting portfolio of instruments and reagents.

In the final episode of the STACCATO podcast series, Ryan (ESR6), Marco (ESR7) and Nikolaus (ESR8) sit down for a casual conversation over Zoom to discuss a more personal side of their STACCATO experience. The initial interaction between ESRs and the development of strong friendships over the years is discussed. The ESRs reflect on the impact of the COVID-19 pandemic on the personal connections made and conclude by giving their thoughts on what the future holds for the STACCATO researchers.

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