Developing high cell density perfusion culture media through single cell analysis.
High cell density perfusion (HCDP) culture has been identified as a highly potential tool for process intensification for the production of biologics. it is very important to get a better understanding of high cell density perfusion cultures and provide new tools for the development of such processes. In particular, the project will aim at creating methods to design the culture medium used for high cell density perfusion process based on mathematical modelling integrating knowledge of single-cell omics.
Brian Ladd studied chemical engineering at the Technical University of Munich. He has experience in mammalian cell culture and upstream process development. In addition to his wet lab experience Brian is also skilled in mathematical modelling using MATLAB.